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Does deficiency of serotonin cause aggression?

Serotonin is a neurotransmitter that is linked with mood regulation. According to several studies, a decrease in levels of Serotonin may lead to aggression.

Impaired serotonin levels are found in many psychiatric conditions such as OCD, addiction, eating disorders, antisocial personality disorder and,etc.

Poor orbitofrontal cortex function is linked to lower levels of serotonin. This phenomenon is present in people with antisocial behavior.

Impulsive aggression is also linked with Low serotonin levels. Impulsive aggression is the key factor in violent and criminal behavior.

Not only the deficiency of serotonin makes one violent but other factors like social, cultural and economic causes plays important role. Although future research is needed to completely understand this phenomenon.

Sources:

https://www.cam.ac.uk/research/news/serotonin-levels-affect-the-brain%E2%80%99s-response-to-anger

https://www.news-medical.net › health Serotonin and Aggression - News Medical

https://www.intechopen.com/chapters/55400

https://www.nature.com/articles/s41598-018-37613-4

3 answers4 replies

7 Comments

erajshahzad99

Jun 18, 2022

interesting findings though

erajshahzad99

Jun 18, 2022

but how can we increase serotonin level?

Daniel Sumner

Jun 18, 2022

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Replying to

That's a great question, I can think of a couple of ways.

One method might be to use that class of drugs known as SSRIs (Selective Serotonin Re-uptake Inhibitors).

Generally when a neuron fires and releases serotonin, some of this serotonin is picked up by other neurons and stimulates further firing. Not all of the serotonin is picked up by these neurons however, and the original firing neuron 'sweeps' up and reabsorbs the serotonin. SSRIs work by halting this reabsorption so serotonin lingers and is available for picking up by other neurons.

Perhaps there may need for artificial more potent forms of serotonin - though one would have to balance this with the fact that neurons may stop releasing serotonin if there is too much.

Jun 18, 2022

Replying to

@erajshahzad99 Regualar exercise and healthy foods like pineapple, eggs and cheese etc can boost serotonin level naturally.

Jun 18, 2022

Replying to

@Daniel Sumner So, we need to find another ways to boost serotonin. Naturally it is hard to produce serotonin quickly, maybe in future we may develop other options.

Daniel Sumner

Jun 17, 2022

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Just spotted this, thanks for sharing this interesting finding of the possible role of serotonin in aggression. It's important as you note the various causes of aggression whether that be learned, via neurotransmitters such as serotonin, or brain topology.

I suppose the serotonin issue is another piece of the overall puzzle of aggression, one looks forward to a time when the puzzle is complete and we can eliminate almost completely the appearance of aggression.

Jun 18, 2022

Replying to

@Daniel Sumner Yes, it is a puzzle indeed. But I think more research with the help of technology, can solve this puzzle.